Assessment of the Morphology of Diabetic Macular Edema Using Optical Coherence Tomography
Kerbala Journal of Medicine,
2013, Volume 6, Issue 2, Pages 1655-1659
Abstractbackground: Diabetic macular edema(DME) is a major cause of visual loss in patients
with diabetes. It usually results from the breakdown of the inner blood–retinal barrier.
Early detection of retinal abnormalities is vital in preventing diabetic macular edema
and subsequent loss of vision. Until recently, the methods available for detecting and
evaluating diabetic macular edema were slit-lamp bio microscopy and stereoscopic
photography, both of which are limited in detecting earlier retinal changes. Optical coherence
tomography (OCT) is a new diagnostic imaging modality that provides high-resolution,
cross-sectional images of the eye. It is proving to be an accurate tool for the early diagnosis,
analysis and monitoring of retinopathy. It allows not only the qualitative diagnosis of diabetic
macular edema, but also the quantitative assessment of edema.
Objective: To verify different morphological types of diabetic macular edema that needs
different treatment strategies.
Patients and methods: A descriptive observational study was done in the OCT unit of
Immam Hussain eye center in Kerbala city from December 2010 to May 2013. OCT done for
420 eyes of 237 patient. Cases with low image quality and cases with other eye disease were
Results: Of 420 eyes,211 eyes (50.4%) have OCT morphological appearance of diffuse
spongiform DME,115 eyes (27.5%) mixed spongiform and cystoid edema, 56 eyes (13.3%)
have cystoid changes, and 38 eyes ( 9% ) showed edema with traction at vitreoretinal
Conclusion: Optical Coherence Tomography based classification of diabetic macular edema
is more accurate in identifying the morphological types that need specific regimes of
treatment and in the follow up the response to treatment.
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