The Effect of Cinnamon Oil on Multi-Drug Resistant Klebseilla Pneumoniae Strains.
Kerbala Journal of Medicine,
2009, Volume 2, Issue 3, Pages 302-307
Abstracthe study was carried out to assess the effect of cinnamon oil on multi-drug resistant (MDR) strains of Klebseilla pneumoniae isolated from various clinical specimens. 150 specimens were collected from Al-Hakeem Teaching Hospital in Al-Najaf Governorate,
Karbala J. Med. Vol.2, No.4,5 July 2008
21 isolates were found to be Klebseilla spp. On further study at the species level only six of these isolates were found to be multi-drug resistant K. pneumoniae. The results of antibiotic sensitivity test showed that most of these isolates were highly resistant (resistance percentage was 50-80%) for the used antibiotics, these strains were defined as a multi-drug resistant K. pneumoniae. The antimicrobial effect of cinnamon oil on these isolates was tested via performing disk diffusion method, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) tests. The results showed a similarity in the antimicrobial actions between this oil and Ceftazidim, Cefotaxim, and Ciprofloxacin in 50% of cases. The study concluded that cinnamon oil could be used as an effective antimicrobial even in case of difficult treated MDR K. pneumoniae as well as it could be used as a safe external ointment in the treatment of infected wounds and vaginal infections.
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