Postprandial lipid profile and Androgen status in polycystic ovarian syndrome (PCOS)
Kerbala Journal of Medicine,
Volume 6, Issue 1, Pages 1497-1505
Abstractobjective:Immunofluorescent microscopyis an important tool for the diagnosis of glomerular diseases. In this study, we focused on using IF technique together with light microscopy and clinical features in the diagnosis of different types of glomerulonephritis. Spectrum of glomerular disease in Iraq is to be studied and compared with other studies in Iraq and other countries.Methods:A total of 58 kidney biopsies were taken for routine LM, while IF technique was done in 56 of them. The study started from 1st of June 2010 to the 1st of June 2012.
Results:Focal segmental glomerulosclerosis(17/58=29.3%) topped thelist followed by minimal change disease(12/58=20.7%).Immunedeposition wasobserved in (21/56=37.5%)cases and the predominant depositwas immunoglobulin G(20/56=35.7%).The pattern ofdeposition was granular in most of the cases either in the glomerular basement membrane and/or in the mesangium except one case where immunoflourecent microscopy showed dominant positive staining (3+) for complement factor 1q in the glomerular mesangium and slightly positive staining for complement factor 3 in the same mesangealareas.(Tow/58=3.4%) cases fulfilled the clinical, serological andhistopathological criteria of lupus nephritis.Conclusion:To obtain a correct diagnosis of glomerulonephritis, we require immunofourescent in parallel with light microscopic examination of renal biopsies and correlation with clinical features, biochemical and serological markers. Clinically, the majority of patients presentedas nephrotic syndrome (44/58=75.9%).
Key words: Immunofluorescence,glomerular disease.
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