Epidemiological and Clinical Study of Visceral Leishmaniasis In Najaf and Karbala Governorate
Kerbala Journal of Medicine,
2007, Volume 1, Issue 1, Pages 124-130
AbstractA retrospective study conducted on (63) patients with V.L. admitted to both Al-Zahraa’ Maternity
and Pediatrics Hospital (MPH) in Al-Najaf and Karbala’ Hospital for Children during the period from Jan.
2005 to Sep. 2006 to shade light on the epidemiological and clinical aspects of V.L. among children from
The number of male cases was 43 (68.2%), while female cases were 20 (31.7%), male to female
ratio was (2.1:1). Most of cases were registered during winter and spring months. 39 (62%) of cases came
from rural areas. The peak ages incidence were1 – 3 years (65%).The commonest presenting features were
fever (100%), splenomegaly (93.6%), and pallor (87.3%).
The consistent laboratory findings were anemia (87.3%) and leucopenia (58.7%). Bone marrow
aspirate were positive in 40 (81.6%) from 49 aspirates taken and 14 (22.2%) patients were treated without
bone marrow aspirate confirmation of the diagnosis
All the patients received sodium stibogluconate (Pentostam)® 20 mg/kg/day for 4 weeks. The main
complications reported were jaundice (9.5%), pneumonia (6.3%), and gastroenteritis (4.7%). Three
relapses (4.7%) have been documented. No deaths were reported.
Keywords: Visceral leishmaniasis, Kala azar
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