Infectious Complications of Visceral Leishmaniasis in Basrah, Southern Iraq…..
Kerbala Journal of Medicine,
Volume 4, Issue 9, Pages 972-979
Abstractobjectives: A prospective study was carried out to study the complications that may be associated with visceral leishmaniasis with special emphasis on any bacterial or parasitic complications.
Methods: The study included 132 in-patient children who were admitted to Basrah Maternity
and Children Hospital and Basrah General Hospital with visceral leishmaniasis
from November 2004 till November 2005.
Direct agglutination test (DAT) and bone marrow examination were used to confirm the
diagnosis. All patients were sent for blood culture, urine culture and stool culture, in addition
to general stool examination.
Results: Among 132 sero-positive cases, Diarrhea with or without vomiting, was found in
75 cases (56.8%), followed by urinary tract infection in 30 (23.4%) of the cases, and
bronchopneumonia in 10 cases (7.5%). The main non-infectious complications were
malnutrition in 86 (65.1%) of the cases, followed by bleeding tendency in 18 cases (13.6%).
Pathogenic bacteria were isolated in 41(31%) out of 132 sero-positive patients. The commonest type of bacteria isolated was Klebsiella (16 isolates) followed by Escherichia coli and Proteus (11 and 9 isolates), respectively. These three types of bacteria represented (78.2%) of total isolates.
Parasitic infections were detected in 44 (33.3%) patients. The commonest parasites
detected were Cryptosporidium parvum (18.9%) and Entamoeba histolytica (13.6%), Giardia
lamblia, Blastocystis hominis, Hymenolypis nana, and Enterobius vermicularis were also
detected but in lower frequency.
Conclusion: From this study we conclude that bacterial infections and pathogenic parasites were confirmed in about one third of VL cases for each; Klebsiella is the most common bacteria reported while Cryptosporidium parvum is the most common parasite.
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