Antipsychotic medications induced extra pyramidal effects
Kerbala Journal of Medicine,
2010, Volume 3, Issue 6, Pages 788-794
Abstractbackground: Antipsychotic drugs are invaluable tools in treating a large
variety of patients with schizophrenia, mood disorders with psychotic features,
senile and other organic psychoses, psychoses associated with Parkinson's
disease. Extrapyramidally mediated movement disorders represent the major set of
adverse effects associated with the use of antipsychotic medications.
Objective: Is to assess the size of the problem of extra pyramidal effects among
chronic patients taking antipsychotic medications.
Method: 100 chronic psychiatric patients attending outpatient department in Diwania
Teaching Hospital to receive their medications were assessed for extra pyramidal side
effect of antipsychotic drugs, using the Extrapyramidal Symptom Rating Scale
(ESRS). The study was conducted between the 8th of January2009 and the 8th of May
Results: the study revealed that 38% of patients on antipsychotic medication have
extra pyramidal effects. The majority of those patients (80%) were taking
Conclusion: the study concludes that extra pyramidal effects are common among
chronic patients on antipsychotic medications.
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