• Evaluation of Serum Cystatin C in Iraqi Cardiovascular Patients
Kerbala Journal of Medicine,
2011, Volume 4, Issue 10, Pages 1063-1066
Abstractbackground: Cystatin C has been reported to be a potent predictor of increased cardiovascular disease mortality. Serum Cystatin C may have a stronger association with mortality and cardiovascular disease than serum Creatinine in patients with normal or mildly reduced kidney function.
Objectives: The aim of this study to
1- Determine the prognostic value of cystatin C in patients with cardiovascular disease (CVD) and compare the observed value with that obtained for healthy controls.
2- Study the correlation between serum cystatin C and creatinine in cardiovascular disease patients.
Patients and Methods: The prospective study included thirty (30) patients admitted to hospital with cardiovascular disease (CVD) slected from Baghdad teaching hospital and twenty-one (21) healthy individuals were included in this study. Fasting serum cystatin C and creatinine were measured in all patients and controls.
Results and Discussion: A significant increased in the level of serum cystatin C concentration was observed in patients with (CVD) as compared with the control group.
Conclusion: Cystatin C is a prognostic biomarker of CVD. A graded association exists between higher serum Cystatin C and increased CVD prevalence in patients without chronic kidney disease (CKD).
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