Prevalence of Endocrine Disorders among Iraqi Women with Menstrual Disturbances
Kerbala Journal of Medicine,
Volume 3, Issue 7, Pages 889-896
Abstractbackground and Objectives: The main causes of menstrual cycle disturbances are
classified as hormonal abnormalities, structural abnormalities, bleeding diatheses,
anovulation, polycystic ovary (PCO), obesity and miscellaneous. In this work, the
prevalence of endocrine disorders in Iraqi women with menstrual disturbances was estimated.
Patients and Methods: One hundred Eighteen females with menstrual disturbances
(delay>10 days occasionally) were included in this study in addition to thirty seven control
women. They were attending to the gynecological clinics for regulation of menstruation
cycle. The study excluded any women taking steroid hormones, neuroleptics, anticoagulants
and cytotoxic agents that frequently lead to menstrual disturbances. Luteinizing hormone
(LH), follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH), prolactine,
total testosterone, estradiol (E2) and progesterone were estimated in the second day of the
menstrual cycle using ELISA technique using a ready for use kits.
Results: The endocrine disorders in menstrual disturbances in the Iraqi women under study
were: 16.1% hypothyroidism, 3.4% hyperthyroidism, 3.4% type 1 diabetes mellitus, and
pituitary tumor was observed in 1.6 % of patients. Additionally, there is a high prevalence of
patients with POCS cases and a high significant increase in the mean of BMI in the patients
when compared with the control women.
Conclusion: Surprisingly, the most common endocrine disorder in the women with menstrual
disturbances group was hypothyroidism. Additionally the PCO is common in these women.
The prevalence of endocrine disorders in irregular women in Iraq was lower than the other
countries and the type of prevalent endocrine disorders is different
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