Evaluation of the Serum and Tissue Levels of Copper and Zinc in Patients with Gynecologic Tumors..................
Kerbala Journal of Medicine,
Volume 2, Issue 4, Pages 497-502
Abstractserum and tissue copper (Cu) and zinc (Zn) levels were determined by atomic absorption
spectrophotometry in 20 women with malignant gynecologic tumors and compared with
levels in 15 with benign gynecologic tumors .A significant (p<0.05) elevation of serum
copper levels in gynecological cancer patients when compared with those of benign
diseases .Estimation of zinc level demonstrated a non statistically significant difference
between malignant and benign gynecologic tumor patients . Determination of tissue copper and
zinc contents revealed a significant (p<0.005) elevations of copper and non significant (p>0.005)
decrease of zinc in malignant tissues with respect to those of benign tumors .In addition to it,
there were essentially correlation between copper and zinc levels in serum and their levels in
tissue in cancer patients but no such correlation in patients with benign tumors.
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