Serum Immunoglobulin Level Derangements in Chronic Lymphocytic Leukemia, Hodgkin's Disease and Non- Hodgkin's Lymphoma
Kerbala Journal of Medicine,
Volume 2, Issue 4, Pages 452-462
AbstractoBjective: to compare the degree of immunoglobulin derangement "hypo or
hypergammaglobulinaemia" among patients with cll, nhl, and hd.
Design: forty three patients with hematologic malignancies attended hematology and
oncology unit in al-sadr teaching hospital in najaf city between february and august 2007, were
evaluated for their serum igg, igm, and iga level with a comparable number of healthy adult
controls. Sixteen patients with cll, thirteen patients with nhl, and fourteen patients with hd were
included in this study.
Results: there is a significant alteration in the level of immunoglobulin among patients with
hematologic malignancies, with a reduced level seen in patients with cll and nhl, and an elevated
level is seen in patients with hd.
Conclusion: immunoglobulin derangement is a common problem in patients with cll, nhl and hd.
Recommondations: larger number of patients, with extension of the study to include igg subsets
is needed for good outcome and better results.
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