Smoking as an Environmental Xenobiotic and Its Effects on Certain Health Parameters
Kerbala Journal of Medicine,
Volume 1, Issue 1, Pages 131-137
AbstractData were drawn in the study from patients seen and/or admitted to Merjan teaching hospital in the
city of Hilla, Babylon governorate and they include:
100 healthy controlled non-smokers and 100 smokers’ non-diabetic and 240 patients with diabetes
mellitus also 100 patients with acute myocardial infarction, 52 patients with bronchogenic carcinoma.
It had been shown that there was statically significant increase in leukocyte count in smokers than in
non-smokers. There is statically significant increase in platelets count between smoker diabetic and
healthy control non-smoker. There are statically significant changes in the level of fibrinogen in
diabetic smoker from non-smoker healthy control and also smoker subject from non-smoker subject.
In patient with acute myocardial infarction we noticed that 89% of them had smoking index above
600. Also we noticed that in patients with bronchogenic carcinoma 87% of them were heavy smokers.
Most of smokers showed significant reduction in peak expiratory flow rate (PEFR) than healthy nonsmokers,
also they showed higher Hb level than non-smoker to extent that venesection in 10 of them
was done to relieve symptoms of secondary polycythemia.
In conclusion tobacco usage through cigarette and other means is the most avoidable risk factors for
several human diseases including cancer.
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