Non – Melanoma Skin Cancers: A Clinical and Histopathological Study
Kerbala Journal of Medicine,
2018, Volume 11, Issue 1, Pages 3943-3947
Abstractbackground: Non – melanoma skin cancer like basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common cutaneous cancer and are associated with multifactorial causes such as environmental and host factors, hence they are not uncommon skin diseases in Iraqi patients.
Aims of the study: This study was conducted to evaluate the topography of lesions and their correlations with gender, age, clinical and histological type and correlation between them.
Patients and methods: A total of 159 patients with in non –melanoma skin cancers were studied in Al-Hussain medical city in a retrospective study during the period from January 2012 to June 2016.
After diagnosing each patient and a careful histopathological examination, statistical analyses were done.
Results: The analysis included 159 patients with non – melanoma skin cancers (NMSCs)
Eighty eight patients with basal cell carcinoma were seen (55.34٪). The majority of patients were in the form of nodular and noduloulcerative &the second most type was basosquamous type.
Clinically, it was the same of nodular type as the majority of cases were diagnosed with this type
Fifty patients with SCCs (31.44 ٪) were seen. Clinically, the patients with SCC presented as a hard indurated plaques or nodules, some were ulcerated.
Nearly all the types may be in the form of well differentiated or moderately well differentiated. Discussion:
NMSCs comprise a significant proportion of all skin cancer patients in the world. BCC is the commonest NMSC worldwide and various studies have reported SCC as the second most prevalent.
Basal cell carcinoma commonly seen on the faces of the middle age or elderly with male to female ratio is about 3: 2 and the incidence increases markedly after age of 40 years.
Squamous cell carcinoma was the next common non – melanoma skin cancers of the face forming about 31.44 ٪ of cases as a potentially lethal form of skin cancer, It can arise from actinic keratosis with a slight male predominance in the male to female ratio 1.17: 1.
The prevalence and distribution of lesions of SCC correlates well with the exposure to ultraviolet radiation.
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