Tear Film Instability in Diabetic Patients
Kerbala Journal of Medicine,
Volume 11, Issue 1, Pages 3918-3922
Abstractbackground: The association between dry eye symptoms and ocular surface disease is becoming more frequent. The recent rise in newly diagnosed cases of diabetes mellitus and the awareness of real complaints of diabetic patients from dryness of the eye and ocular discomfort are responsible for the recent increase in the number of patients and frequency of their consultations to the outpatient departments.
Aims of the study: To investigate the changes of tear film and ocular surface in diabetic patients.
Design and method: A case control study carried out in the eye clinic of Al-Sadr Teaching hospital in holy Najaf city for 12 months. It included 100 eyes of fifty patients of Type 2 Diabetes Mellitus (Cases) and 100 eyes of fifty healthy individual (Controls). After exclusion of patients with history of systemic diseases with ocular manifestations affecting tear secretion, abnormalities in the cornea, conjunctiva, or eyelid, and secondary ocular and systemic disease, the remaining diabetic cases are 72 and control cases are 89. Different symptoms included; character of irritation whether it was burning, foreign body sensation or sand gritty feeling. All the individuals underwent routine general physical examination and thorough ophthalmological examination followed by measuring tear film meniscus height, tear film breakup time (BUT), presence or absence of tear film debris.
Results: There is significant difference between diabetics and non-diabetics in presence of normal or abnormal tear meniscus height. There is also significant difference between diabetics and non-diabetics regarding normal and abnormal tear film breakup time. However, there are no significant differences between diabetic and control group in the presence or absence of tear film debris.
Conclusion: Tear film stability is decreased in diabetic patients. These results sug¬gest that diabetic patients are more prone to suffer¬ing from dry eye symptoms than normal subjects.
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