Thyroid Dysfunction during Pregnancy
Kerbala Journal of Medicine,
2018, Volume 11, Issue 1, Pages 3894-3902
Abstractbackground: Pregnancy is the time of hormonal changes which may result in endocrine disorders. Thyroid disorders are common clinical problem during pregnancy in which subclinical hypothyroidism is the most common thyroid disorders. Maternal thyroid dysfunction may result in short-term and long- term harm to the mother and child.
Objective: To study the prevalence of thyroid disorder during pregnancy and to follow the correlation between (TSH, FT3, and FT4) with BMI
Materials and Method: A cross sectional study involved 120 pregnant women in second and third trimester (apparently normal) between (19-42) years.
The participants were collected randomly from outpatient unit of Al-Zahraa teaching hospital in AL-Najaf AL-Ashraf, detailed history and data for pregnant women were recorded (including maternal age, gestational age ,medical history of thyroid disease and history of abortion and infertility) .Pregnant women with history of thyroid disease were excluded from the study. Serum TSH, FT3 and FT4 were measured for all pregnant women participated in study
Results: The prevalence of thyroid disorder during pregnancy was 20.8% out of which 20(16.6%) had SCH and 2(1.6%) had OH. Hyperthyroidism detected in 3(2.5%) pregnant women all of them had subclinical hyperthyroidism. and there was a positive correlation between TSH, FT3 with BMI and negative correlation of FT4 with BMI, also maternal age don’t affect thyroid function status significantly (p value < 0.05).and there was no significant relation between thyroid disorder and history of abortion or infertility (p value < 0.05)
There is a high prevalence of hypothyroidism during pregnancy and the majority is subclinical hypothyroidism .BMI was correlated positively with TSH and FT3 and negatively with FT4.
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