Clinicopathological Spectrum of Renal Biopsies in Children a Multicenter Study in Baghdad-Iraq
Kerbala Journal of Medicine,
Volume 10, Issue 1, Pages 2641-2649
Abstractbackground: Renal biopsy is a very important diagnostic tool for many kidney diseases which play important role in the diagnosis, management and prognosis of kidney diseases.
Aim of study: To study the indications, histopathological findings, and complications of renal biopsies in multicenter in Baghdad-Iraq.
Materials and Methods: In this retrospective and descriptive study, we included renal biopsies done in multicenter in Baghdad-Iraq, from 1st of January 2014 to 31 of December 2016, which was 120 patients up to 17 years of age
Results: Out of 120 patients, 68 cases (56.6%) were males, and 52 cases (43.3%) were females, steroid resistant nephrotic syndrome was the main indication of renal biopsy 42% followed by acute glomerulonephritis 19% and then evidence of systemic lupus erythematosus 15%, minimal change nephrotic syndrome was the most common primary kidney disease 39% followed by focal segmental glomerulosclerosis 31%. And lupus nephritis was the most common secondary kidney disease 83%, hematuria and mild pain at site of biopsy was the most common complications of renal biopsy 31.4% and 40% respectively.
Conclusion: Renal biopsy is useful in diagnosis, assess level of chronicity, management, and prognosis of kidney diseases. Steroid resistant nephrotic syndrome remain the most common indication for renal biopsy, minimal change disease and focal segmental glomerulosclerosis is the most common histopathological lesions in primary kidney diseases, lupus nephritis is the most common secondary kidney diseases. Renal biopsy under ultrasound guidance is safe with self-limited complications in form of hematuria and mild pain at site of biopsy.
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